Charles T. Stier, Jr., Ph.D., is a bona fide pharmacologist. For ten years, he has served as the basic science executive editor for the American Journal of Hypertension, which is one of the top three hypertension journals in the world and has edited more than 2,000 manuscripts. Dr. Stier has an extensive research background inclusive of numerous grants from the National Institutes of Health, the American Heart Association and Pharmaceutical Industry.

The Department of Pharmacology at New York Medical College is a center of excellence for Eicosanoid Research. As a faculty member in this department for more than 40 years, Dr. Stier is an expert in the area of Eicosanoids. These areas of academic expertise and experience have allowed him to have a positive impact on the learners and members of the NYMC community in his roles as director of the dental and graduate pharmacology courses as well as his many teaching roles in the NYMC School of Medicine.

Education

• B.S., Chemistry, State University of New York at Stony Brook
• M.S., M.Phil., Pharmacology, Columbia University Vagelos College of Physicians and Surgeons
• Ph.D., Pharmacology, Columbia University Vagelos College of Physicians and Surgeons
• NIH Postdoctoral Fellowship, Renal Physiology/Nephrology, University of North Carolina at Chapel Hill

Areas of Expertise

• Pharmacology
• Kidney
• Hypertension
• Stroke
• Eicosanoids

Honors and Awards

• Outstanding Faculty Award, The Graduate School of Basic Medical Sciences, New York Medical College

Research

• American Heart Association, North Carolina Affiliate Grant-in-Aid. Effect of dopamine on glomerular ultrafiltration dynamics. 7/1/81-6/30/82. 
• New York Medical College Grant-in-Aid. Intrarenal Formation of Serotonin from its Amino Acid Precursors. 8/1/82-7/31/83. 
• Pharmaceutical Manufacturers Association Foundation Research Starter Grant. Role of thromboxane in water balance, renal hemodynamics and development of hypertension spontaneously hypertensive rats (SHR). 1/1/83-12/31/84. 
• American Heart Association, National Center. Thromboxane, fluid balance and renal function in hypertension. 
• National Institutes of Health. Role of eicosanoids in renin release and renal function. 
• National Institutes of Health. Thromboxane in severe hypertension. 12/1/85-11/30/88.
• American Heart Association, National Center. Stroke prevention and reversal of renal dysfunction in SHRSP. 7/1/89-6/30/92.
• National Institutes of Health (NHLBI). Prevention of stroke and kidney dysfunction by ACE inhibition. 7/1/89-6/30/92.
• American Heart Association, New York State Affiliate, Inc. Angiotensin and vascular damage in stroke-prone spontaneously hypertensive rats. 7/1/92-6/30/95.
• National Institutes of Health (NHLBI) Prevention of stroke and kidney dysfunction by ACE inhibition. 12/1/93-11/30/97.
• American Heart Association, New York State Affiliate, Inc. Role of mineralocorticoids in the vascular pathology of stroke-prone hypertensive rats. 7/1/98-6/30/01.
• National Institutes of Health (NHLBI) Prevention of stroke and kidney dysfunction by ACE inhibition. 9/30/99-8/31/03.
• National Institutes of Health (NHLBI) Program Project Grant. Hormonal regulation of blood pressure. Co-Director of Core C: Genetics and Phenotyping. 4/1/2011-03/31/2016.

Publications

• Stier CT, Gupte S. "Commentary on Expression of Exogenous Epithelial Sodium Channel Beta Subunit in the Mouse Middle Cerebral Artery Increases Pressure-Induced Constriction." American journal of hypertension, 34(11), (2021) 1143-1144. doi: 10.1093/ajh/hpab134
• Schragenheim J, Bellner L, Cao J, et. al. "EET enhances renal function in obese mice resulting in restoration of HO-1-Mfn1/2 signaling, and decrease in hypertension through inhibition of sodium chloride co-transporter." Prostaglandins & other lipid mediators, 137(), (2018) 30-39. doi: 10.1016/j.prostaglandins.2018.05.008
• Camp R, Stier CT Jr, Serova LI, et. al. "Cardiovascular responses to intranasal neuropeptide Y in single prolonged stress rodent model of post-traumatic stress disorder." Neuropeptides, 67(), (2018) 87-94. doi: 10.1016/j.npep.2017.11.006
• Carroll MA, Kang Y, Chander PN, et. al. "Azilsartan is associated with increased circulating angiotensin-(1-7) levels and reduced renovascular 20-HETE levels." American journal of hypertension, 28(5), (2015) 664-71. doi: 10.1093/ajh/hpu201
• Li J, Stier CT, Chander PN, et. al. "Pharmacological manipulation of arachidonic acid-epoxygenase results in divergent effects on renal damage." Frontiers in pharmacology, 5(), (2014) 187. doi: 10.3389/fphar.2014.00187
• Stier CT. "Vascular effects of high-salt intake." Journal of hypertension, 31(3), (2013) 472-3. doi: 10.1097/HJH.0b013e32835e8de1
• Stier CT Jr. "Serotonin and dopamine in essential hypertension." American journal of hypertension, 26(2), (2013) 151. doi: 10.1093/ajh/hps085

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Professional Service

• Session Chair, Winter Eicosanoid Conference, Session Chair
• Abstract Reviewer, American Heart Association Scientific Session
• Session Chair, American Heart Association Scientific Sessions
• AHA Northeast One Study Group, Integrated Cardiovascular Biology
• Special Emphasis Panel for review of NIH grant applications
• SBIR Study Section Neurodegenerative Diseases, Silver Springs/Washington DC
• Editorial Board: American Journal of Hypertension
• Editorial Board: Journal of Hypertension
• Editorial Board: Cardiovascular Drug Reviews
• Executive Editor: American Journal of Hypertension
• Editorial Board: American Journal of Hypertension
• Guest Editor: American Journal of Hypertension

Memberships and Affiliations

• Fellow, American Heart Association Council for High Blood Pressure Research
• American Society of Pharmacology and Experimental Therapeutics
• American Society of Hypertension
• American Federation for Clinical Research
• American Heart Association, Council on Hypertension
• American Heart Association, Council on Kidney in Cardiovascular Disease
• The New York Society of Nephrology
• Eastern Hypertension Society
• American Society of Nephrology

Teaching Responsibilities

• Dental Pharmacology Course Director and Lecturer
• Graduate Pharmacology: Course Director and Lecturer
• NYMC School of Medicine: CV Module – Lecturer and Small Group Facilitator
• NYMC School of Medicine: Renal Module – Lecturer
• NYMC School of Medicine: Module 2 – Lecturer

Hobbies

• Travel
• Camping
• Fishing
• Numismatics