Contact
Morgan Anderson-Crannage, Ph.D., is an investigator with expertise in inflammation, immunology, and computational biology. Together with the Division of Pediatric Hematology, Oncology, and Stem Cell Transplantation, he conducts research on genetic engineering of natural killer cell immunotherapeutics for the treatment of childhood cancer. With a strong foundation in both wet-lab and computational methodologies, his work emphasizes the integration of high-dimensional genomic datasets with functional validation to uncover biologically meaningful mechanisms.
His doctoral training was completed at New York Medical College in the lab of Mitchell S. Cairo, M.D., where his work centered on applying single-cell RNA sequencing to understand pathologies underlying Recessive Dystrophic Epidermolysis Bullosa and identify novel therapeutic targets. Prior to his academic appointment, Dr. Anderson-Crannage held positions at Hackensack University Medical Center and the Vitalant Stem Cell Laboratory, where he gained experience in clinical and translational research settings.
Education
Ph.D., Cell Biology and Anatomy, New York Medical College
Bachelor of Science, Biology, SUNY Purchase College
Areas of Expertise
Cell Biology
Immunology
Publications
- Hirani R, Anderson-Crannage M, Goldberg C, Lodescar RJ, Etienne M. Gender Disparity Trends in Surgical Specialties: A 12-Year Analysis. J Surg Res. 2025 Dec;316:151-157. doi: 10.1016/j.jss.2025.10.042. Epub 2025 Nov 28. PubMed PMID: 41317592.
- Anderson-Crannage M, Nyström A, Hirani R, Schaefer E, Hochberg B, Kann R, Pan J, Tian M, Zhu H, Luo W, Ayello J, Cairo MS, Liao Y. Inflammatory modulation by cord blood stem cells prevented digit deformation in recessive dystrophic epidermolysis bullosa. Mol Ther. 2025 Nov 5;33(11):5427-5441. doi: 10.1016/j.ymthe.2025.08.038. Epub 2025 Aug 28. PubMed PMID: 40883988; PubMed Central PMCID: PMC12628145.
- Anderson-Crannage M, Hirani R, Pan J, Ramirez M, Tian M, Nyström A, Cairo MS, Liao Y. Knockout of IL-1R1 Reduced Inflammation and Improved Survival in a Mouse Model of Recessive Dystrophic Epidermolysis Bullosa. J Invest Dermatol. 2025 Jul;145(7):1813-1816. doi: 10.1016/j.jid.2025.01.010. Epub 2025 Jan 23. PubMed PMID: 39863134.
- Anderson-Crannage M, Cairo MS, Liao Y. Reading through the nonsense: Gentamicin and ELX-02 as rescuing therapies for epidermolysis bullosa. Mol Ther Nucleic Acids. 2024 Dec 10;35(4):102368. doi: 10.1016/j.omtn.2024.102368. eCollection 2024 Dec 10. PubMed PMID: 39629116; PubMed Central PMCID: PMC11613416.
- Anderson-Crannage M, Ascensión AM, Ibanez-Solé O, Zhu H, Schaefer E, Ottomanelli D, Hochberg B, Pan J, Luo W, Tian M, Chu Y, Cairo MS, Izeta A, Liao Y. Inflammation-mediated fibroblast activation and immune dysregulation in collagen VII-deficient skin. Front Immunol. 2023;14:1211505. doi: 10.3389/fimmu.2023.1211505. eCollection 2023. PubMed PMID: 37809094; PubMed Central PMCID: PMC10557493.
- Zhu Q, Mishra A, Park JS, Liu D, Le DT, Gonzalez SZ, Anderson-Crannage M, Park JM, Park GH, Tarbay L, Daneshvar K, Brandenburg M, Signoretti C, Zinski A, Gardner EJ, Zheng KL, Abani CP, Hu C, Beaudreault CP, Zhang XL, Stanton PK, Cho JH, Velíšek L, Velíšková J, Javed S, Leonard CS, Kim HY, Chung S. Human cortical interneurons optimized for grafting specifically integrate, abort seizures, and display prolonged efficacy without over-inhibition. Neuron. 2023 Mar 15;111(6):807-823.e7. doi: 10.1016/j.neuron.2022.12.014. Epub 2023 Jan 9. PubMed PMID: 36626901; PubMed Central PMCID: PMC10023356.
Teaching Responsibilities
- Medical Histology Instructor, NYMC 2022-2024
