Malik Bisserier, Ph.D., joined NYMC from the Cardiovascular Research Institute at the Icahn School of Medicine at Mount Sinai in New York City. Dr. Bisserier's postdoctoral work uncovered a new epigenetic mechanism underlying the loss of BMPR2 in pulmonary arterial hypertension. His work has been published in high-impact journals, including Circulation, Circulation Research, Cardiovascular Research, Blood, Journal of the American College of Cardiology, and Molecular Therapy. Dr. Bisserier is a member of the American Thoracic Society, American Heart Association, International Society of Heart Research, and the Pulmonary Vascular Research Institute and he currently serves as Guest Editor of several journals.

Dr. Bisserier has been awarded several prestigious recognitions, including the Cournand and Comroe Early Career Investigator Award from the American Heart Association. His lab aims to further investigate the transcriptional and epigenetic alterations in pulmonary arterial hypertension with the ultimate goal to develop new therapeutic strategies for prevention and treatment.

 

Education

• B.Sc., Biotechnology, University of Bordeaux
• M.Sc., Life Sciences, University of Bordeaux
• Ph.D., Biology, Health & Biotechnology, University of Toulouse
• Postdoc., Epigenetics, at Yale University
• Postdoc., Gene therapy in Pulmonary arterial hypertension, Cardiovascular Research Institute at Icahn School of Medicine at Mount Sinai

Honors and Awards

• Cournand & Comroe Early Career Investigator Award, American Heart Association, 2020
• Abstract Scholarship, American Thoracic Society, 2020
• Abstract Award, Pulmonary Vascular Research Institute (PVRI), 2020
• Best Research Award, Pulmonary Vascular Research Institute (PVRI), 2020
• Young Investigator Travel Grant, Pulmonary Vascular Research Institute (PVRI), 2020
• 3CPR Junior Investigator Travel Grant, American Heart Association (AHA), 2019
• Research Fellowship, Phillippe Foundation, 2018
• Award for Best Oral Presentation, French Society of Cardiology (GRRC), 2015
• Award for Best Poster Presentation, French Society of Cardiology (GRRC) 2015
• Travel grant, European Atherosclerosis Society (EAS), 2015
• Jury award, highest academic distinction, University of Toulouse (France), 2015
• Award for Best Poster Presentation, French Society of Cardiology (GRRC), 2014

Publications

• Rai AK, Muthukumaran NS, Nisini N, et. al. "Transcriptome wide changes in long noncoding RNAs in diabetic ischemic heart disease." Cardiovascular diabetology, 23(1), (2024) 365. doi: 10.1186/s12933-024-02441-6
• Jankowski K, Lemay SE, Lozano-Ojalvo D, et. al. "Pharmacological Inhibition of Epac1 Protects against Pulmonary Fibrosis by Blocking FoxO3a Neddylation." bioRxiv : the preprint server for biology, (), (2024) . pii: 2024.09.13.612935. doi: 10.1101/2024.09.13.612935
• Pizzo E, Cervantes DO, Ripa V, et. al. "The cAMP/PKA signaling pathway conditions cardiac performance in experimental animals with metabolic syndrome." Journal of molecular and cellular cardiology, 196(), (2024) 35-51. doi: 10.1016/j.yjmcc.2024.09.002
• Bisserier M, Martelotto LG, El-Osta A, et. al. "Editorial: RNA-chromatin interactions: biology, mechanism, disease, and therapeutics-volume 2." Frontiers in genetics, 15(), (2024) 1461574. doi: 10.3389/fgene.2024.1461574
• Jankowski K, Jagana V, Bisserier M, et. al. "Switch-Independent 3A: An Epigenetic Regulator in Cancer with New Implications for Pulmonary Arterial Hypertension." Biomedicines, 12(1), (2023) . doi: 10.3390/biomedicines12010010
• Brojakowska A, Jackson CJ, Bisserier M, et. al. "Lifetime evaluation of left ventricular structure and function in male ApoE null mice after gamma and space-type radiation exposure." Frontiers in physiology, 14(), (2023) 1292033. doi: 10.3389/fphys.2023.1292033
• Santin Y, Formoso K, Haidar F, et. al. "Inhalation of acidic nanoparticles prevents doxorubicin cardiotoxicity through improvement of lysosomal function." Theranostics, 13(15), (2023) 5435-5451. doi: 10.7150/thno.86310

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Professional Service

• Defense Jury Member doctoral and graduate dissertation/thesis
• Reviewer for Granting Agencies
• Organizer of Research-in-Progress talk and Journal Club
• Peer reviewer
• Guest editor
• Laboratory Safety Officer