Malik Bisserier, Ph.D., joined NYMC from the Cardiovascular Research Institute at the Icahn School of Medicine at Mount Sinai in New York City. Dr. Bisserier's postdoctoral work uncovered a new epigenetic mechanism underlying the loss of BMPR2 in pulmonary arterial hypertension. His work has been published in high-impact journals, including Circulation, Circulation Research, Cardiovascular Research, Blood, Journal of the American College of Cardiology, and Molecular Therapy. Dr. Bisserier is a member of the American Thoracic Society, American Heart Association, International Society of Heart Research, and the Pulmonary Vascular Research Institute and he currently serves as Guest Editor of several journals.
Dr. Bisserier has been awarded several prestigious recognitions, including the Cournand and Comroe Early Career Investigator Award from the American Heart Association. His lab aims to further investigate the transcriptional and epigenetic alterations in pulmonary arterial hypertension with the ultimate goal to develop new therapeutic strategies for prevention and treatment.
Education
- Ph.D., Biology, Health & Biotechnology, University of Toulouse
- Postdoc., Epigenetics, Yale University
- Postdoc., Gene Therapy in Pulmonary Arterial Hypertension, Cardiovascular Research Institute at Icahn School of Medicine at Mount Sinai
- M.Sc., Life Sciences, University of Bordeaux
- B.Sc., Biotechnology, University of Bordeaux
Honors and Awards
- Cournand & Comroe Early Career Investigator Award, American Heart Association, 2020
- Abstract Scholarship, American Thoracic Society, 2020
- Abstract Award, Pulmonary Vascular Research Institute (PVRI), 2020
- Best Research Award, Pulmonary Vascular Research Institute (PVRI), 2020
- Young Investigator Travel Grant, Pulmonary Vascular Research Institute (PVRI), 2020
- 3CPR Junior Investigator Travel Grant, American Heart Association (AHA), 2019
- Research Fellowship, Phillippe Foundation, 2018
- Award for Best Oral Presentation, French Society of Cardiology (GRRC), 2015
- Award for Best Poster Presentation, French Society of Cardiology (GRRC) 2015
- Travel grant, European Atherosclerosis Society (EAS), 2015
- Jury award, highest academic distinction, University of Toulouse (France), 2015
- Award for Best Poster Presentation, French Society of Cardiology (GRRC), 2014
Publications
- Zakharyan R, Stepanyan A, Minasyan A, et. al. "Genomic Instability and Clonal Hematopoiesis in the Deep-Space Environment: The Role of Sex-Chromosome Asymmetry and High-LET Radiation." Current stem cell reports, 12(), (2026) . pii: 3. doi: 10.1007/s40778-026-00255-8
- Brojakowska A, Bisserier M, Eskandari A, et. al. "Cardiovascular risks and hazards associated with deep space exploration." Communications medicine, 6(1), (2026) . doi: 10.1038/s43856-026-01728-x
- Toro V, Mougin M, Brossat C, et. al. "Correction to: Breast Cancer Reveals Latent BMPR2-Related Susceptibility to Pulmonary Hypertension." Circulation, 153(21), (2026) e1362. doi: 10.1161/CIR.0000000000001451
- Pizzo E, Cervantes DO, Piccinini G, et. al. "Notch1 deletion reduces arrhythmogenic remodeling after myocardial infarction." Heart rhythm, (), (2026) . pii: S1547-5271(26)02240-X. doi: 10.1016/j.hrthm.2026.03.1957
- Meste O, Sun MY, Cervantes DO, et. al. "A custom analysis of R-R interval properties reveals alterations in the brain-heart axis in experimental animals with metabolic syndrome." Heart rhythm O2, 7(2), (2025) 354-371. doi: 10.1016/j.hroo.2025.11.025
- Jankowski K, Ghosh A, Ochoa MT, et. al. "Sotatercept Reverses SIN3a Deficiency-Driven PAH by Reprogramming BMPR2/TGF-β-HIF-1α Signaling Pathways." bioRxiv : the preprint server for biology, (), (2026) . pii: 2026.02.03.703590. doi: 10.64898/2026.02.03.703590
- Toro V, Mougin M, Brossat C, et. al. "Breast Cancer Reveals Latent BMPR2-Related Susceptibility to Pulmonary Hypertension." Circulation, 153(7), (2026) 516-533. doi: 10.1161/CIRCULATIONAHA.125.079067
Professional Service
- Defense Jury Member doctoral and graduate dissertation/thesis
- Reviewer for Granting Agencies
- Organizer of Research-in-Progress talk and Journal Club
- Peer reviewer
- Guest editor
- Laboratory Safety Officer
