Mitchell S. Cairo is a professor of pediatrics, medicine, pathology, microbiology and immunology and cell biology and anatomy, and associate chairman of the Department of Pediatrics at New York Medical College. He earned his medical degree at the the University of Wisconsin and University of California, San Francisco, and he completed a pediatric hematology/oncology fellowship at Indiana University. A researcher and a practicing physician, Dr. Cairo is also chief of pediatric hematology, oncology and stem cell transplantation, and director of the Children and Adolescent Cancer and Blood Diseases Center at Maria Fareri Children’s Hospital at Westchester Medical Center. His work focuses on cancer genetics, tumor immunology, transplantation biology, stem cell biology and regenerative medicine. 

Areas of Expertise

• Malignant and Non-Malignant Hematology
• Oncology
• Immunology
• Hematopoietic Stem Cell Transplantation
• Lymphoma and Leukemia
• Cell Biology
• Basic, Clinical, and Translational Research
• Pediatrics
• Genetics

Education

• B.A., University of Wisconsin
• M.D., University of California, San Francisco (UCSF)
• Chief Resident, University of California, San Francisco (UCSF)
• Residency, Pediatrics, University of California, Los Angeles (UCLA) Harbor General Hospital
• Fellowship, Pediatric Hematology/Oncology, Indiana University

Research

Dr. Cairo has more than 475 peer reviewed publications, more than 1,300 national and international abstract presentations, more than 50 book chapters and edited two textbooks. He is an international leader in the biology and treatment of childhood and adolescent lymphomas and leukemias, stem cell transplantation, developmental therapeutics, experimental hematopoiesis and immunology and stem cell biology and regenerative therapy. Dr. Cairo was a pioneer in the use of cord blood stem cells for treating pediatric malignant and non-malignant disease, the use of cord blood stem cells for potential regenerative therapy and stem cell transplantation for sickle cell disease.

Publications

• Luo W, Gardenswartz A, Hoang H, et. al. "Combinatorial immunotherapy of anti-MCAM CAR-modified expanded natural killer cells and NKTR-255 against neuroblastoma." Molecular therapy. Oncology, 32(4), (2024) 200894. doi: 10.1016/j.omton.2024.200894
• Luo W, Hoang H, Zhu H, et. al. "Circumventing resistance within the Ewing sarcoma microenvironment by combinatorial innate immunotherapy." Journal for immunotherapy of cancer, 12(9), (2024) . doi: 10.1136/jitc-2024-009726
• Paudel SN, Hutzen BJ, Miller KE, et. al. "Myelomodulatory treatments augment the therapeutic benefit of oncolytic viroimmunotherapy in murine models of malignant peripheral nerve sheath tumors." Frontiers in immunology, 15(), (2024) 1384623. doi: 10.3389/fimmu.2024.1384623
• Paudel SN, Hutzen BJ, Miller KE, et. al. "Corrigendum: Myelomodulatory treatments augment the therapeutic benefit of oncolytic viroimmunotherapy in murine models of malignant peripheral nerve sheath tumors." Frontiers in immunology, 15(), (2024) 1456897. doi: 10.3389/fimmu.2024.1456897
• Luo W, Hoang H, Miller KE, et. al. "Combinatorial macrophage induced innate immunotherapy against Ewing sarcoma: Turning "Two Keys" simultaneously." Journal of experimental & clinical cancer research : CR, 43(1), (2024) 193. doi: 10.1186/s13046-024-03093-w
• Chu Y, Nayyar G, Tian M, et. al. "Efficiently targeting neuroblastoma with the combination of anti-ROR1 CAR NK cells and N-803 in vitro and in vivo in NB xenografts." Molecular therapy. Oncology, 32(2), (2024) 200820. doi: 10.1016/j.omton.2024.200820
• Gardenswartz A, Cairo MS. "Therapy for Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma in Children, Adolescents, and Young Adults." Journal of the National Comprehensive Cancer Network : JNCCN, 22(5), (2024) . pii: e247006. doi: 10.6004/jnccn.2024.7006

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Memberships and Affiliations

• Society of Pediatric Research (SPR)
• American Pediatrics Society (APS)
• American Academy of Pediatrics (AAP)
• Eastern Society for Pediatric Research (ESPR)
• American Society of Hematology (ASH)
• American Society of Clinical Oncology (ASCO)
• American Society for Blood and Marrow Transplantation (ASBMT)
• American Association of Immunologists (AAI)
• International Society for Experimental Hematology (ISEH)
• American Association for Cancer Research (AACR)
• American Society of Pediatric Hematology/Oncology (ASPHO)
• Society for Industrial and Organizational Psychology (SIOP)
• Pediatric Blood and Marrow Transplant Consortium (PBMTC)
• Coalition of Geriatric Services (COG)

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