After completing his second fellowship, Raymond Dattwyler, M.S., M.D., began his academic career at Massachusetts General Hospital/Harvard Medical School, moving to Stony Brook University SOM in 1981. At Stony Brook, his interests in infectious diseases and immunology led him to Lyme disease, a rapidly emerging disease on Long Island during the 1980s. To address this growing problem of tick-borne infections, he established the Lyme Disease and Tick-Borne Disease Center at Stony Brook University and served as its director for more than 20 years.

While at Stony Brook, Dr. Dattwyler was promoted to professor of medicine and chief of clinical immunology/allergy. In 2005, he was invited to join New York Medical College's faculty. In collaboration with new colleagues at New York Medical College, Dr. Dattwyler continued his research on the laboratory diagnosis, treatment and prevention of vector borne infectious disease including post 9/11 biothreat agents. He has a strong background in diagnostic laboratory immunology and in mucosal immunology. This has led him to research involving the development of vaccines and immunodiagnostics for Lyme disease and other vector borne infectious diseases. 

Over the course of his career, Dr. Dattwyler has received multiple NIH research grants, RO1s, SBIR Phase 1 and SBIR Phase 2 awards. He has published more than 100 papers and holds multiple patents addressing Lyme disease diagnostics and vaccines. He has served on multiple committees and study sections for the FDA, CDC, DOD and NIH.

Areas of Expertise

• Molecular biology
• Cell biology
• Clinical immunology
• Allergy and rheumatology
• Lyme disease research

Education

• M.S., State University of New York at Buffalo
• M.D., State University of New York at Buffalo
• Internship, University of Wisconsin at Madison
• Residency, Tufts New England-Medical Center
• Fellowship, Immunology, Mayo Clinic
• Fellowship, Allergy and Clinical Immunology, Harvard Medical School and Massachusetts General Hospital

Honors and Awards

• Best Doctors in America 1998-Present

Publications

• Ghosh R, Joung HA, Goncharov A, et. al. "Rapid single-tier serodiagnosis of Lyme disease." Nature communications, 15(1), (2024) 7124. doi: 10.1038/s41467-024-51067-5
• Dattwyler RJ, Arnaboldi PM. "Vaccination hesistancy in Lyme borreliosis." The Lancet. Infectious diseases, 24(9), (2024) 945-947. doi: 10.1016/S1473-3099(24)00221-4
• Ghosh R, Joung HA, Goncharov A, et. al. "Single-tier point-of-care serodiagnosis of Lyme disease." bioRxiv : the preprint server for biology, (), (2023) . pii: 2023.06.14.544508. doi: 10.1101/2023.06.14.544508
• Arnaboldi PM, Katseff AS, Sambir M, et. al. "Linear Peptide Epitopes Derived from ErpP, p35, and FlaB in the Serodiagnosis of Lyme Disease." Pathogens (Basel, Switzerland), 11(8), (2022) . doi: 10.3390/pathogens11080944
• Dattwyler RJ, Gomes-Solecki M. "The year that shaped the outcome of the OspA vaccine for human Lyme disease." NPJ vaccines, 7(1), (2022) 10. doi: 10.1038/s41541-022-00429-5
• Arnaboldi PM, D'Arco C, Hefter Y, et. al. "Detection of IFN-γ Secretion in Blood Samples Collected Before and After Treatment of Varying Stages of Lyme Disease." Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 73(8), (2021) 1484-1491. doi: 10.1093/cid/ciab503
• Joung HA, Ballard ZS, Wu J, et. al. "Point-of-Care Serodiagnostic Test for Early-Stage Lyme Disease Using a Multiplexed Paper-Based Immunoassay and Machine Learning." ACS nano, 14(1), (2020) 229-240. doi: 10.1021/acsnano.9b08151

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Professional Service

• Vaccine committee American Academy of Allergy, Asthma and Immunology
• Consultant, Regional Tick-Borne Disease Resource Center
  Stony Brook Southampton Hospital
• NIH/NIAID Lyme Disease Research Planning Committee, Washington, DC, 1994-2000
• Tick Borne Disease Institute – State of New York Department of Health, Albany, NY, 1990-2004
• CDC/ASTPHLD Lyme Disease Serology Committee
• CDC Lyme disease case definition Committee
• FDA Consultant Anti Infective Drugs Committee, 1996-2009 
• FDA CEBA, 1997-2001
• Ad HOC, various NIH study sections
• NIH/NIAID IMM-G study section, 2004-2006
• Co-Chair NIH, CDC Conference on the Laboratory Diagnosis of Lyme and other tick-borne Infectious diseases, 2007
• Member, DOD Treat Reduction study section, 2007-2014
• Member, Grant review committee AAAAI, 2006-2016
• ACP representative, NIH food allergy guideline panel
• IDSA Lyme disease Treatment Guideline Committee

Memberships and Affiliations

• Clinical and Laboratory Immunology
• American Board of Allergy and Immunology
• American Board of Internal Medicine

Teaching Responsibilities

• Pathology, Microbiology, and Immunology