Jan Geliebter, Ph.D.
Jan Geliebter, Ph.D., has had an interest in science at the age of eight when his parents bought him a chemistry set. Following postdoctoral training in the molecular genetics of the Major Histocompatibility Complex with Dr. Stanley Nathenson at the Albert Einstein College of Medicine, Dr. Geliebter's career has focused on the molecular pathogenesis and immunology of cancer, as well as immunological diseases.
Over the last 19 years, with the help of supportive chairs, supportive faculty and graduate students, Dr. Geliebter has been the director of the medical microbiology course for second-year medical students. During this time, he has maintained an active research laboratory and mentored residents, graduate students, medical students, M.D.-Ph.D. students, undergraduate students, and high school students.
Education
- B.Sc., Biology, Hebrew University of Jerusalem
- Ph.D., Microbiology and Immunology, State University of New York (SUNY) Downstate Medical Center
Honors and Awards
- NYMC Teaching and Mentoring Award; 2002, 2004, 2006, 2007, 2008, 2009, 2011, 2012, 2013, 2014, 2015, 2016, 2017, 2018, 2019, 2020, 2021
- AMWA Gender Equity Award, 2004
- Alpha Omega Alpha, Faculty Initiate, 2006
- NYMC Student Senate Award; 2014, 2017, 2018
- Robert Goldstein Society of Teachers Award, 2014
Research
Dr. Geliebter's laboratory uses RNASeq to interrogate the landscape of gene expression alteration in PTC in clinical samples. By comparing PTC and samples of normal tissues from the same patients, the researchers have gained insight into the molecular changes driving PTC, as well as potential therapeutic targets. As men have a lower incidence of PTC than women, the lab is concentrating on the role of androgens in the etiology and progression of PTC. The results indicate that androgens exert an anti-proliferative effect and result in a G1-S block in the cancer cell cycle.
Publications
- Gupta A, Carnazza M, Jones M, et. al. "Correction: Gupta et al. Androgen Receptor Activation Induces Senescence in Thyroid Cancer Cells. Cancers 2023, 15, 2198." Cancers, 16(21), (2024) . doi: 10.3390/cancers16213636
- Maskey AR, Kopulos D, Kwan M, et. al. "Berberine Inhibits the Inflammatory Response Induced by Staphylococcus aureus Isolated from Atopic Eczema Patients via the TNF-α/Inflammation/RAGE Pathways." Cells, 13(19), (2024) . doi: 10.3390/cells13191639
- Musa I, Yang N, Breslin J, et. al. "Inhibition of Myeloma Cell Function by Cannabinoid-Enriched Product Associated With Regulation of Telomere and TP53." Integrative cancer therapies, 23(), (2024) 15347354241267979. doi: 10.1177/15347354241267979
- DeSouza NR, Jarboe T, Carnazza M, et. al. "Long Non-Coding RNAs as Determinants of Thyroid Cancer Phenotypes: Investigating Differential Gene Expression Patterns and Novel Biomarker Discovery." Biology, 13(5), (2024) . doi: 10.3390/biology13050304
- DeSouza NR, Nielsen KJ, Jarboe T, et. al. "Dysregulated Expression Patterns of Circular RNAs in Cancer: Uncovering Molecular Mechanisms and Biomarker Potential." Biomolecules, 14(4), (2024) . doi: 10.3390/biom14040384
- Yang N, Srivastava K, Chen Y, et. al. "Sustained silencing peanut allergy by xanthopurpurin is associated with suppression of peripheral and bone marrow IgE-producing B cell." Frontiers in immunology, 15(), (2024) 1299484. doi: 10.3389/fimmu.2024.1299484
- DeSouza NR, Quaranto D, Carnazza M, et. al. "Interactome of Long Non-Coding RNAs: Transcriptomic Expression Patterns and Shaping Cancer Cell Phenotypes." International journal of molecular sciences, 24(12), (2023) . doi: 10.3390/ijms24129914
Professional Service
- Education & Curriculum Committee (ECC)
- 1st & 2nd Year Subcommittee of ECC
- Executive Committee of the Faculty Senate
- Faculty Compensation
- Faculty Senate – Vice President
- First Year Student Promotions
- Second Year Student Promotions
- SAST Committee
- Library & Academic Support
- Curriculum Redesign for Medical School
- Strategic Planning for Medical School
- Search Committee for Chair for Department of Pathology and Microbiology/Immunology Department
- Search for Vice Chair for Research for Department of Pathology and Microbiology/Immunology Department IRB – Oncology
- GSBMS – Student Appeals Board
- NYMC Commencement Speaker – Chair
- GSBMS – New Course Committee
- GSBMS – Student Appeals Committee
Teaching Responsibilities
- Medical Microbiology
- Basic Immunology
- Advanced Immunology
- Immunopharmacology
- Introduction to Pathology
- Dental Microbiology
- Transition to Clerkship
- Transition to Fourth Year
- COVID-19 Bootcamp