Julian M. Stewart, M.D., Ph.D., directs the Center for Hypotension, which has had NIH funding for 24 years. He is trained in medicine, integrative physiology, and computer based biophysical methods. Dr. Stewart's laboratory has been studying orthostatic intolerance in conscious humans for more than 20 years with a particular focus on circulatory regulation in orthostatic intolerance (OI). Chronic OI is better known as postural tachycardia syndrome (POTS). His research has contributed to literature regarding measurements of systemic vascular resistance, cardiac output, and venous capacitance as well as microvascular properties. Recently, Dr. Stewart's research has been focused on connections between hypocapnia, hypercapnia, hyperventilation, and impaired cognition, cardiovagal baroreflexes, cerebral autoregulation, splanchnic vasoconstriction and venoconstriction, and enhanced sympathetic activity in OI patients.

Education

• A.B., Physics, Cornell University
• M.D., University of Chicago
• Ph.D., University of Chicago
• Postdoc, Pediatric Cardiology, New York Hospital-Cornell University
• Residency, Physiology/Biophysics, NYU Medical Center
• Fellowship, Pediatric Cardiology, New York Hospital-Cornell University

Areas of Expertise

• Pediatrics/Pediatric Cardiology
• Hypotension
• DOD Gulf War Syndrome
• CFS/Fibromyalgia

Research

Research interests include computational circulatory physiology investigating vascular and cardiac properties in animal model systems as well as during diagnostic procedures such as cardiac catheterization and flow-volume monitoring and redistribution in critically ill infants and children. Correlative work studying the relation of cardiovascular properties to nitric oxide physiology is in progress. Recent work has also included connections of peripheral flow and muscle pump activity with osteoporosis, and contractual work with the Department of Defense related to muscular dystrophy.

Publications

• Pfaff JL, Eden SK, Kundu S, et. al. "Depression and Heart Failure in US Veterans." JAMA network open, 8(5), (2025) e259246. doi: 10.1001/jamanetworkopen.2025.9246
• Nataliansyah MM, Alimi YR, Barry L, et. al. "A qualitative study of micro and macroaggression experienced by Black surgical trainees through an anonymous reporting." American journal of surgery, (), (2025) 116371. doi: 10.1016/j.amjsurg.2025.116371
• Schmidt AC, Fairlie L, Hellström E, et. al. "BCG Revaccination for the Prevention of Mycobacterium tuberculosis Infection." The New England journal of medicine, 392(18), (2025) 1789-1800. doi: 10.1056/NEJMoa2412381
• Singh P, Wilson KT, Varghese L, et. al. "Case Report-Cytopathological Diagnosis of Metastatic Squamous Cell Carcinoma in Vitreous Fluid." Cytopathology : official journal of the British Society for Clinical Cytology, (), (2025) . doi: 10.1111/cyt.13507
• Stewart JJ, Robinson JL, Chen JZ, et. al. "Nitrites for Urinary Tract Infection-Time to Say Goodbye?" JAMA internal medicine, (), (2025) . doi: 10.1001/jamainternmed.2025.0973
• Abd Alrahman F, Abratenko P, Abrego-Martinez N, et. al. "Search for a Hidden Sector Scalar from Kaon Decay in the Dimuon Final State at ICARUS." Physical review letters, 134(15), (2025) 151801. doi: 10.1103/PhysRevLett.134.151801
• Chan BK, Stanley GL, Kortright KE, et. al. "Personalized inhaled bacteriophage therapy for treatment of multidrug-resistant Pseudomonas aeruginosa in cystic fibrosis." Nature medicine, (), (2025) . doi: 10.1038/s41591-025-03678-8

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Professional Service

• CDC-NIH Committee on Chronic Fatigue in Adolescents
• NIH/NIAID Special Emphasis Panel
• Ad Hoc Reviewer CVS-A
• Reviewer CICS
• Associate Chair IRB