Dazhong Xu, Ph.D. joined the faculty at New York Medical College as Assistant Professor of Pathology and Head of Flow Cytometry Core Laboratory in 2014. Dr. Xu served as Vice Chair of Research of the Department of Pathology from 2017 to 2021. In 2020, he was promoted to associate professor of pathology, microbiology, and immunology. Prior to NYMC, Dr. Xu worked at New York University School of Medicine as a Research Assistant Professor and Tuft University School of Medicine as an Instructor of Medicine. 

Education

• B.S., Biology, Nanjing University
• M.S., Zoology, University of Florida
• Ph.D., Biomedical Sciences, Wright State University
• Postdoctoral training: Massachusetts General Hospital/Harvard Medical School and Tufts Medical Center

Honors and Awards

• 2005-Jay N. Cohn New Investigator Award in Basic Science, The Heart Failure Society of America
• 2005-Travel Award, The Heart Failure Society of America
• 2004-Travel Award, The Heart Failure Society of America
• 2002-National Research Service Award Individual Postdoctoral Fellowship

Research

Dr. Xu's laboratory is interested in the molecular and cellular biology of cancer, with a focus on lung carcinogenesis induced by environmental and occupational carcinogens. A major goal of the lab is to identify novel molecular mechanisms underlying carcinogenesis and cancer progression. The laboratory employs various state-of-the-art molecular, cellular, and genetic tools, as well as mouse models, to achieve its research goals.

Publications

• Alur A, Phillips J, Xu D, et. al. "Effects of hexavalent chromium on mitochondria and their implications in carcinogenesis." Journal of environmental science and health. Part C, Toxicology and carcinogenesis, 42(2), (2024) 109-125. doi: 10.1080/26896583.2024.2301899
• Li C, Edeni D, Platkin S, et. al. "Effect of Gene 33/Mig6/ERRFI1 on hexavalent chromium-induced transformation of human bronchial epithelial cells depends on the length of exposure." Journal of environmental science and health. Part C, Toxicology and carcinogenesis, 40(3-4), (2022) 227-247. doi: 10.1080/26896583.2022.2147358
• Xu J, Xu D, Hu Q, et. al. "Immune regulatory functions of biologically active proteins from edible fungi." Frontiers in immunology, 13(), (2023) 1034545. doi: 10.3389/fimmu.2022.1034545
• Xu D, Li C. "Gene 33/Mig6/ERRFI1, an Adapter Protein with Complex Functions in Cell Biology and Human Diseases." Cells, 10(7), (2021) . doi: 10.3390/cells10071574
• Xu D, Li C. "Regulation of the SIAH2-HIF-1 Axis by Protein Kinases and Its Implication in Cancer Therapy." Frontiers in cell and developmental biology, 9(), (2021) 646687. doi: 10.3389/fcell.2021.646687
• Jin H, Xue L, Mo L, et. al. "Downregulation of miR-200c stabilizes XIAP mRNA and contributes to invasion and lung metastasis of bladder cancer." Cell adhesion & migration, 13(1), (2019) 236-248. doi: 10.1080/19336918.2019.1633851
• Yang Z, Hou Z, Xu D, et. al. "[Multifunctional Cervical Health Care Pillow]." Zhongguo yi liao qi xie za zhi = Chinese journal of medical instrumentation, 42(5), (2018) 341-344. doi: 10.3969/j.issn.1671-7104.2018.05.009

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Professional Service

• 2021 – 2021 Co-Chair, Vice Chair of Research Search Committee, PMI

Memberships and Affiliations

• Member, Institutional Animal Care and Use Committee, SOM
• Member, Institutional Biosafety Committee, SOM
• Member, PhD Admission Committee, GSBMS
• Member, Membership Committee, GSBMS
• Member, Course and Program Evaluation Committee, GSBMS

Teaching Responsibilities

• Selected Topics in Cancer Biology
• Introduction to Pathology