Areas of Expertise

• Rapid diagnostics
• Antimicrobials
• Microbial pathogenesis
• Molecular epidemiology
• Bacterial and fungal genomics

Education

• Ph.D., Medical Microbiology, Delhi University
• Postdoc., Infectious Diseases, University of Cincinnati
• Postdoc., Infectious Diseases, Universidad Complutense de Madrid

Research

Dr. Chaturvedi's laboratory focuses on applying whole-genome sequencing (WGS) to study the emergence and spread of bacterial and fungal pathogens, developing and validating WGS methods to enhance understanding of infectious disease dynamics and advance diagnostic tests for pathogenic fungi. They are committed to integrating new technologies into clinical microbiology. In antifungal drug research, they have pioneered rapid, sensitive susceptibility testing methods with support from pharmaceutical companies and have led efforts to standardize these methods across multiple laboratories. Their work in molecular epidemiology has significantly contributed to understanding fungal and bacterial pathogens in the U.S., including rapid outbreak investigations, characterization of unknown pathogens, and defining pathogen virulence, bridging the gap between basic and translational science.

Dr. Chaturvedi's lab focuses on the following areas:

Genomics and Devices – Dr. Chaturvedi's lab is interested in the applications of the whole-genome sequencing (WGS) to understand the emergence and dissemination of bacterial and fungal pathogens. They have developed and validated WGS methods and applied deep sequencing to understand infectious disease dynamics. They are passionate about introduction of new diagnostic tests to address the challenges of emerging and re-emerging pathogenic fungi and aim to promote the adaptation of new technologies by the clinical microbiology laboratories.

Antifungals Drugs – Dr. Chaturvedi's lab has a sustained record of productivity in innovation of laboratory testing of antifungal drugs. With support from major pharmaceutical companies, they developed several rapid and sensitive methods for susceptibility testing of antifungals alone and in combination. They have also participated and lead numerous multi-laboratory studies to standardize antifungal susceptibility testing methods for the clinical laboratories.

Epidemiology of Microbial Diseases – Dr. Chaturvedi's lab has made several major contributions to molecular epidemiology of fungal and bacterial pathogens in the United States. Many collaborative publications described new laboratory tools, undocumented clinical conditions, and occurrence of pathogens outside of known endemic areas. They lead rapid outbreak investigations, characterizations of unknown pathogens, defined pathogen virulence, and provided a bridge between basic and translational science.

Previous professional positions: New York State Department of Health, California Department of Public Health, and Yale University School of Medicine

Publications

• Jacobs SE, Chaturvedi V. "CAF to the Rescue! Potential and Challenges of Combination Antifungal Therapy for Reducing Morbidity and Mortality in Hospitalized Patients With Serious Fungal Infections." Open forum infectious diseases, 11(11), (2024) ofae646. doi: 10.1093/ofid/ofae646
• Rhodes J, Jacobs J, Dennis EK, et. al. "What makes Candida auris pan-drug resistant? Integrative insights from genomic, transcriptomic, and phenomic analysis of clinical strains resistant to all four major classes of antifungal drugs." Antimicrobial agents and chemotherapy, 68(10), (2024) e0091124. doi: 10.1128/aac.00911-24
• Sharma A, Wu L, Bloom S, et. al. "RWC Update: Dislocated DSEK Flap; Ellipsoid Zone as a Surrogate Efficacy Endpoint in Clinical Trials; Retinal Tear Associated With Lattice Degeneration." Ophthalmic surgery, lasers & imaging retina, 55(8), (2024) 425-428. doi: 10.3928/23258160-20240716-01
• Ciechomska AD, Chaturvedi V, Thabah M, et. al. "Integrating point-of-care ultrasound into rheumatology practice." Polish archives of internal medicine, 134(10), (2024) . pii: 16815. doi: 10.20452/pamw.16815
• Chaturvedi V, Falk M, Björklund S, et. al. "Monoolein-Based Wireless Capacitive Sensor for Probing Skin Hydration." Sensors (Basel, Switzerland), 24(14), (2024) . doi: 10.3390/s24144449
• Maji S, Ghosh SK, Jha JK, et. al. "A prospective observational study to assess the epidemiological profile of multiple primary cancers in Eastern India." Journal of cancer research and therapeutics, 20(3), (2024) 888-892. doi: 10.4103/jcrt.JCRT_1603_20
• Chockalingam P, Geetha TS, Nair S, et. al. "Results of comprehensive genetic testing in patients presenting to a multidisciplinary inherited heart disease clinic in India." Indian heart journal, 76(4), (2024) 260-267. doi: 10.1016/j.ihj.2024.07.002

View All Publications

Memberships and Affiliations

• Editor-in-Chief, Mycopathologia