Contact
Meena Jhanwar-Uniyal, Ph.D., started exploring brains at a very early age during her educational training in science. Her first brush with discovery happened while working as an M.S. student, where she demonstrated that hypothalamic neurotransmitters, such as GABAergic system, play an important role in stress. Dr. Jhanwar-Uniyal's second discovery was her Ph.D. work, where she established the role of the Hippocampus in the Memory and Learning Process as it pertains to Serotonergic. These findings secured her an award for the best science prize and secured her a post-doc position at The Rockefeller University where she established the biochemical/molecular analysis of the distribution of brain catecholaminergic receptors (a1 and a2; ß; and DA1 and DA2) in the microdissected brain tissue samples and demonstrated a close link and rapid interaction between a circulating hormone (corticosterone) and brain neurotransmitter activity (a2-noradrenergic receptors controlling behavior. Following a short post-doctoral training, Dr. Jhanwar-Uniyal joined the faculty and rose to the rank of independent investigator at the Rockefeller University. Additionally, Dr. Jhanwar-Uniyal had identified the sequence-specific promoter/enhancer region of the first breast cancer gene, the BRCA1 gene, in Human Breast Cancer and showed the role of tumor suppressor gene p53 and its interaction with PLK3 during cell cycle regulation.
At New York Medical College, Dr. Jhanwar-Uniyal established a laboratory in the Department of Neurosurgery, where she worked on precision medicine relating mTOR/PI3K pathway in GBM, genetic/therapeutic aspects of medulloblastoma, and genetics/mechanistic aspects of metastatic brain tumors. Dr. Jhanwar-Uniyal developed and used novel aspects of regenerative medicine in spinal cord injury, and her group established the understanding of cancer stem cells to use as a therapeutic target. Dr. Jhanwar-Uniyal's laboratory also established the use of the innovative stem cell therapy in the treatment of spinal cord injury. Many of her mentees have received prestigious fellowships and awards.
Education
- M.S., Ph.D., Molecular Neuroscience, Banaras Hindu University and Academy of Sciences
- Post-doc, The Rockefeller University
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Publications
Teaching Responsibilities
- Rotating medical students are taught genetic basis of precision medicine, regenerative medicine and Cancer and neuronal stem cells.
