Jian Li, Ph.D., completed his graduate study in Dr. David Gilmour's lab at Penn State University. His thesis work using biochemical and next-generation sequencing approaches uncovered mechanisms underlying promoter-proximal pausing of RNA polymerase II, an important regulatory step of eukaryotic transcription. Dr. Li then moved to Dr. Rick Morimoto’s lab at Northwestern University for his postdoctoral training, where he started using the nematode C. elegans as a model. His work discovered the transcriptional program of HSF1, the key regulator of cellular heat shock response, in animal development independent of temperature stress. Dr. Li established his own lab at Oklahoma Medical Research Foundation in 2017. His lab uses both animal and cellular models and combines genetics, cellular biology and multi-omics (functional genomics, transcriptomics, proteomics and metabolomics) to understand protein homeostasis (proteostasis) and stress response pathways in reproduction, aging and cancer. Dr. Li joined the faculty of NYMC in 2022.
Education
- B.S., Biotechnology, Peking University
- Ph.D., Biochemistry, Pennsylvania State University
- Postdoctoral training, Northwestern University
Honors and Awards
- 2020: NIH Maximizing Investigators' Research Award (MIRA)
- 2016-2017: Ruth L. Kirschstein National Research Service Award
- 2014-2016: Postdoctoral Fellowship, BrightFocus Foundation for Alzheimer's Disease Research
- 2014-2016: Postdoctoral Grant Award, Chicago Biomedical Consortium
- 2014: Postdoctoral Fellowship, National Ataxia Foundation
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Publications
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