Julian M. Stewart, M.D., Ph.D., directs the Center for Hypotension, which has had NIH funding for 24 years. He is trained in medicine, integrative physiology, and computer-based biophysical methods.
Dr. Stewart's laboratory has been studying orthostatic intolerance in conscious humans for more than 20 years, with a particular focus on circulatory regulation in orthostatic intolerance (OI). Chronic OI is better known as postural tachycardia syndrome (POTS). His research has contributed to the literature regarding measurements of systemic vascular resistance, cardiac output, and venous capacitance as well as microvascular properties. Recently, Dr. Stewart's research has been focused on connections between hypocapnia, hypercapnia, hyperventilation, impaired cognition, cardiovagal baroreflexes, cerebral autoregulation, splanchnic vasoconstriction and venoconstriction, and enhanced sympathetic activity in OI patients.
Education
- Fellowship, Pediatric Cardiology, New York Hospital-Cornell University
- Residency, Physiology/Biophysics, NYU Medical Center
- M.D., University of Chicago
- Ph.D., University of Chicago
- A.B., Physics, Cornell University
- Postdoc, Pediatric Cardiology, New York Hospital-Cornell University
Areas of Expertise
- Pediatrics/Pediatric Cardiology
- Hypotension
- DOD Gulf War Syndrome
- CFS/Fibromyalgia
Research
Research interests include computational circulatory physiology, investigating vascular and cardiac properties in animal model systems, as well as during diagnostic procedures such as cardiac catheterization and flow-volume monitoring, and redistribution in critically ill infants and children. Correlative work studying the relation of cardiovascular properties to nitric oxide physiology is in progress. Recent work has also included connections of peripheral flow and muscle pump activity with osteoporosis, and contractual work with the Department of Defense related to muscular dystrophy.
Publications
- Zhang Y, Wei C, Stewart JM, et. al. "Transient vitreous opacity following combined intravitreal injection of pegcetacoplan and faricimab-svoa in patients with neovascular age-related macular degeneration and geographic atrophy." American journal of ophthalmology case reports, 42(), (2026) 102545. doi: 10.1016/j.ajoc.2026.102545
- Stewart JB, Belanger AM, Watt CA, et. al. "Assessing the Relationship Between Blubber Thickness and Adipocyte Size in Beluga Whales." Animals : an open access journal from MDPI, 16(4), (2026) . pii: 650. doi: 10.3390/ani16040650
- Stewart JE. "The Meaning of Life in a Universe Whose Ultimate Origins are Unknown." Bio Systems, (), (2026) 105733. doi: 10.1016/j.biosystems.2026.105733
- Mann T, Stewart J, Safavi AH, et. al. "Evaluation of Organs-at-Risk Sparing for Glioblastoma Patients Using a Small-Margin Weekly Adaptive Protocol on a 1.5T MR-Linac: UNITED trial Organs-at-Risk Sparing." International journal of radiation oncology, biology, physics, (), (2026) . pii: S0360-3016(26)00404-9. doi: 10.1016/j.ijrobp.2026.02.217
- Stewart J, Lu J, Goudie A, et. al. "Short-Term Outcomes and Sex-Based Analysis Following Chest Pain Presentations to Emergency Departments in Western Australia-An AUS-MOCHA Substudy." Emergency medicine Australasia : EMA, 38(1), (2026) e70235. doi: 10.1111/1742-6723.70235
- Zeng Q, Wang M, Wang E, et. al. "Sex and APOE genotype specific brain regional vulnerability to Alzheimer's Disease." GeroScience, (), (2026) . doi: 10.1007/s11357-025-02089-4
- Fritz NE, Stewart JC. "Moving the Movement System Forward in Neurologic Physical Therapy." Journal of neurologic physical therapy : JNPT, (), (2026) . doi: 10.1097/NPT.0000000000000551
Professional Service
- CDC-NIH Committee on Chronic Fatigue in Adolescents
- NIH/NIAID Special Emphasis Panel
- Ad Hoc Reviewer CVS-A
- Reviewer, Center for Interdisciplinary Cardiovascular Sciences
