Julian M. Stewart, M.D., Ph.D., directs the Center for Hypotension, which has had NIH funding for 24 years. He is trained in medicine, integrative physiology, and computer-based biophysical methods.
Dr. Stewart's laboratory has been studying orthostatic intolerance in conscious humans for more than 20 years, with a particular focus on circulatory regulation in orthostatic intolerance (OI). Chronic OI is better known as postural tachycardia syndrome (POTS). His research has contributed to the literature regarding measurements of systemic vascular resistance, cardiac output, and venous capacitance as well as microvascular properties. Recently, Dr. Stewart's research has been focused on connections between hypocapnia, hypercapnia, hyperventilation, impaired cognition, cardiovagal baroreflexes, cerebral autoregulation, splanchnic vasoconstriction and venoconstriction, and enhanced sympathetic activity in OI patients.
Education
- Fellowship, Pediatric Cardiology, New York Hospital-Cornell University
- Residency, Physiology/Biophysics, NYU Medical Center
- M.D., University of Chicago
- Ph.D., University of Chicago
- A.B., Physics, Cornell University
- Postdoc, Pediatric Cardiology, New York Hospital-Cornell University
Areas of Expertise
- Pediatrics/Pediatric Cardiology
- Hypotension
- DOD Gulf War Syndrome
- CFS/Fibromyalgia
Research
Research interests include computational circulatory physiology, investigating vascular and cardiac properties in animal model systems, as well as during diagnostic procedures such as cardiac catheterization and flow-volume monitoring, and redistribution in critically ill infants and children. Correlative work studying the relation of cardiovascular properties to nitric oxide physiology is in progress. Recent work has also included connections of peripheral flow and muscle pump activity with osteoporosis, and contractual work with the Department of Defense related to muscular dystrophy.
Publications
- Stewart JD, Ramirez DX, Leon-Reyes A, et. al. "Land Use Change Reshapes Climate-Driven Diversity Patterns of Tropical Arbuscular Mycorrhizal Fungi." Molecular ecology, 35(2), (2026) e70253. doi: 10.1111/mec.70253
- Roche SD, Kamolloh K, Thuo N, et. al. "Implementing long-acting injectable HIV pre-exposure prophylaxis services at private pharmacies in Kenya: client, pharmacy provider and key stakeholder perspectives on potential challenges and opportunities." BMJ global health, 11(1), (2026) . doi: 10.1136/bmjgh-2025-019210
- Kadam PR, Lim J, Dizani M, et. al. "Coarse-Grained Modeling and Simulation of Multistranded RNA Nanostars." Chem & bio engineering, 3(1), (2025) 37-48. doi: 10.1021/cbe.5c00093
- Stewart JW, Barth BA, Rojas I, et. al. "The utility of artificial intelligence in visualization of pediatric gastrointestinal mucosa." Frontiers in pediatrics, 13(), (2026) 1739000. doi: 10.3389/fped.2025.1739000
- Zekarias K, Alutaibi M, Stewart J, et. al. "Endoscopic ultrasound-guided radiofrequency ablation of pancreatic insulinoma." BMJ case reports, 19(1), (2026) . pii: e269256. doi: 10.1136/bcr-2025-269256
- King MG, Alousis N, Collins T, et. al. "Symptom Trajectories of People With Low Back Pain Presenting to the Emergency Department: Insights From the BACK TrAC Digital Care Pathway." Journal of emergency nursing, (), (2026) . pii: S0099-1767(26)00007-3. doi: 10.1016/j.jen.2025.12.016
- Stewart J, Hassan S, Al-Bermani A, et. al. "Management of Bilateral Endogenous Methicillin-Sensitive Staphylococcus aureus (MSSA) Endophthalmitis Without Intravitreal Sampling or Injection." Cureus, 17(12), (2025) e99807. doi: 10.7759/cureus.99807
Professional Service
- CDC-NIH Committee on Chronic Fatigue in Adolescents
- NIH/NIAID Special Emphasis Panel
- Ad Hoc Reviewer CVS-A
- Reviewer, Center for Interdisciplinary Cardiovascular Sciences
