Julian M. Stewart, M.D., Ph.D., directs the Center for Hypotension, which has had NIH funding for 24 years. He is trained in medicine, integrative physiology, and computer-based biophysical methods.
Dr. Stewart's laboratory has been studying orthostatic intolerance in conscious humans for more than 20 years, with a particular focus on circulatory regulation in orthostatic intolerance (OI). Chronic OI is better known as postural tachycardia syndrome (POTS). His research has contributed to the literature regarding measurements of systemic vascular resistance, cardiac output, and venous capacitance as well as microvascular properties. Recently, Dr. Stewart's research has been focused on connections between hypocapnia, hypercapnia, hyperventilation, impaired cognition, cardiovagal baroreflexes, cerebral autoregulation, splanchnic vasoconstriction and venoconstriction, and enhanced sympathetic activity in OI patients.
Education
- Fellowship, Pediatric Cardiology, New York Hospital-Cornell University
- Residency, Physiology/Biophysics, NYU Medical Center
- M.D., University of Chicago
- Ph.D., University of Chicago
- A.B., Physics, Cornell University
- Postdoc, Pediatric Cardiology, New York Hospital-Cornell University
Areas of Expertise
- Pediatrics/Pediatric Cardiology
- Hypotension
- DOD Gulf War Syndrome
- CFS/Fibromyalgia
Research
Research interests include computational circulatory physiology, investigating vascular and cardiac properties in animal model systems, as well as during diagnostic procedures such as cardiac catheterization and flow-volume monitoring, and redistribution in critically ill infants and children. Correlative work studying the relation of cardiovascular properties to nitric oxide physiology is in progress. Recent work has also included connections of peripheral flow and muscle pump activity with osteoporosis, and contractual work with the Department of Defense related to muscular dystrophy.
Publications
- Alizada S, Al Qudah H, Vu T, et. al. "Ultrasound imaging features of cervical lymph nodes with melanoma metastasis compared with benign cervical nodes." Melanoma research, (), (2026) . doi: 10.1097/CMR.0000000000001107
- Lázaro Weiss JJ, Santana-Ufret VA, Hamner JJ, et. al. "Use of Intraperitoneal Bupivacaine After Prolapse Surgery: A Double-Blind RCT." Urogynecology (Philadelphia, Pa.), 32(6), (2026) 726-734. doi: 10.1097/SPV.0000000000001729
- Starr LR, Conway CC, Rnic K, et. al. "Toward next-generation stress generation research: Expert consensus methodological guidelines." Journal of psychopathology and clinical science, (), (2026) . doi: 10.1037/abn0001113
- Holbrooks JS, Loveless CA, Vogler KA, et. al. "Conditional deletion of human STN1 leads to telomere dysfunction, genome instability and proliferation defects." Journal of cell science, 139(10), (2026) . pii: jcs264269. doi: 10.1242/jcs.264269
- Ahmed K, Rizvi A, Chen C, et. al. "Endoscopic ultrasound-guided fine-needle biopsy for diagnosis of SMARCA4-deficient undifferentiated thoracic tumor." Proceedings (Baylor University. Medical Center), 39(3), (2025) 530-533. doi: 10.1080/08998280.2025.2591559
- Ghosh S, Stewart J, Ruschin M, et. al. "Influence of FLAIR inclusion on patterns-of-failure and outcomes in glioblastoma: results from the UNITED prospective adaptive radiotherapy trial." Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, (), (2026) 111579. doi: 10.1016/j.radonc.2026.111579
- White MC, Lange PT, Stewart J, et. al. "NEK2 drives pathogenesis, drug resistance, and LMP1 expression in EBV-positive non-Hodgkin lymphoma." Proceedings of the National Academy of Sciences of the United States of America, 123(20), (2026) e2535550123. doi: 10.1073/pnas.2535550123
Professional Service
- CDC-NIH Committee on Chronic Fatigue in Adolescents
- NIH/NIAID Special Emphasis Panel
- Ad Hoc Reviewer CVS-A
- Reviewer, Center for Interdisciplinary Cardiovascular Sciences
