Julian M. Stewart, M.D., Ph.D., directs the Center for Hypotension, which has had NIH funding for 24 years. He is trained in medicine, integrative physiology, and computer-based biophysical methods.
Dr. Stewart's laboratory has been studying orthostatic intolerance in conscious humans for more than 20 years, with a particular focus on circulatory regulation in orthostatic intolerance (OI). Chronic OI is better known as postural tachycardia syndrome (POTS). His research has contributed to the literature regarding measurements of systemic vascular resistance, cardiac output, and venous capacitance as well as microvascular properties. Recently, Dr. Stewart's research has been focused on connections between hypocapnia, hypercapnia, hyperventilation, impaired cognition, cardiovagal baroreflexes, cerebral autoregulation, splanchnic vasoconstriction and venoconstriction, and enhanced sympathetic activity in OI patients.
Education
- Fellowship, Pediatric Cardiology, New York Hospital-Cornell University
- Residency, Physiology/Biophysics, NYU Medical Center
- M.D., University of Chicago
- Ph.D., University of Chicago
- A.B., Physics, Cornell University
- Postdoc, Pediatric Cardiology, New York Hospital-Cornell University
Areas of Expertise
- Pediatrics/Pediatric Cardiology
- Hypotension
- DOD Gulf War Syndrome
- CFS/Fibromyalgia
Research
Research interests include computational circulatory physiology, investigating vascular and cardiac properties in animal model systems, as well as during diagnostic procedures such as cardiac catheterization and flow-volume monitoring, and redistribution in critically ill infants and children. Correlative work studying the relation of cardiovascular properties to nitric oxide physiology is in progress. Recent work has also included connections of peripheral flow and muscle pump activity with osteoporosis, and contractual work with the Department of Defense related to muscular dystrophy.
Publications
- Bondi CD, Hartman HL, Gilbert JL, et. al. "Tubular Epithelia-Specific Deletion of MCP-1 Does Not Afford Protection Against Adriamycin-Induced Kidney Injury." International journal of molecular sciences, 27(5), (2026) . doi: 10.3390/ijms27052432
- Stewart JJP. "Computational chemistry methods based on MNDO and tools for improving their accuracy." Journal of molecular modeling, 32(4), (2026) . doi: 10.1007/s00894-026-06653-3
- Stewart JH 4th. "Building Bridges: A National Mentorship Network as a Model for Surgical Education." Journal of the American College of Surgeons, (), (2026) . doi: 10.1097/XCS.0000000000001833
- Mahon N, Hays LMC, Coy E, et. al. "Views on consent approaches used in emergency and critical care research: a rapid, systematic review." Trials, (), (2026) . doi: 10.1186/s13063-026-09592-9
- Stewart JH. "From Description to Action: A Roadmap for Dismantling Cancer Disparities in Surgical Oncology." Annals of surgical oncology, (), (2026) . doi: 10.1245/s10434-026-19382-x
- Reid N, Hewlett N, Hayes N, et. al. "Australian Guidelines for Assessment and Diagnosis of Fetal Alcohol Spectrum Disorder: Overview of the Development Process and Revised Diagnostic Criteria." The Medical journal of Australia, 224(3), (2026) e70159. doi: 10.5694/mja2.70159
- Cascino TM, Herron G, Richards B, et. al. "Understanding of Prognosis and Estimation of Mortality in Ambulatory Patients With Heart Failure." JAMA network open, 9(3), (2026) e260328. doi: 10.1001/jamanetworkopen.2026.0328
Professional Service
- CDC-NIH Committee on Chronic Fatigue in Adolescents
- NIH/NIAID Special Emphasis Panel
- Ad Hoc Reviewer CVS-A
- Reviewer, Center for Interdisciplinary Cardiovascular Sciences
