Julian M. Stewart, M.D., Ph.D., directs the Center for Hypotension, which has had NIH funding for 24 years. He is trained in medicine, integrative physiology, and computer-based biophysical methods.
Dr. Stewart's laboratory has been studying orthostatic intolerance in conscious humans for more than 20 years, with a particular focus on circulatory regulation in orthostatic intolerance (OI). Chronic OI is better known as postural tachycardia syndrome (POTS). His research has contributed to the literature regarding measurements of systemic vascular resistance, cardiac output, and venous capacitance as well as microvascular properties. Recently, Dr. Stewart's research has been focused on connections between hypocapnia, hypercapnia, hyperventilation, impaired cognition, cardiovagal baroreflexes, cerebral autoregulation, splanchnic vasoconstriction and venoconstriction, and enhanced sympathetic activity in OI patients.
Education
- Fellowship, Pediatric Cardiology, New York Hospital-Cornell University
- Residency, Physiology/Biophysics, NYU Medical Center
- M.D., University of Chicago
- Ph.D., University of Chicago
- A.B., Physics, Cornell University
- Postdoc, Pediatric Cardiology, New York Hospital-Cornell University
Areas of Expertise
- Pediatrics/Pediatric Cardiology
- Hypotension
- DOD Gulf War Syndrome
- CFS/Fibromyalgia
Research
Research interests include computational circulatory physiology, investigating vascular and cardiac properties in animal model systems, as well as during diagnostic procedures such as cardiac catheterization and flow-volume monitoring, and redistribution in critically ill infants and children. Correlative work studying the relation of cardiovascular properties to nitric oxide physiology is in progress. Recent work has also included connections of peripheral flow and muscle pump activity with osteoporosis, and contractual work with the Department of Defense related to muscular dystrophy.
Publications
- Ortiz Cano HG, Hadfield R, Gomez T, et. al. "Correction: Ecological-niche modeling reveals current opportunities for Agave dryland farming in Sonora, Mexico and Arizona, USA." PloS one, 21(2), (2026) e0343010. doi: 10.1371/journal.pone.0343010
- Olalde I, Altena E, Bourgeois Q, et. al. "Lasting Lower Rhine-Meuse forager ancestry shaped Bell Beaker expansion." Nature, (), (2026) . doi: 10.1038/s41586-026-10111-8
- Egoavil A, Rajagopal J, Jayanti R, et. al. "Transcatheter Aortic Valve Replacement Facilitated by ShortCut Leaflet Laceration After Failed BASILICA." JACC. Cardiovascular interventions, 19(3), (2026) 383-385. doi: 10.1016/j.jcin.2025.10.060
- Du Toit S, Haag K, Tomlinson M, et. al. "Early childhood and early adolescent predictors of internalising symptoms in adolescents: findings from a longitudinal study in a high-risk South African environment." Social psychiatry and psychiatric epidemiology, (), (2026) . doi: 10.1007/s00127-026-03048-w
- Mulholland B, Chitiz L, Wallace R, et. al. "Patterns of ongoing thought in the real world and their links to mental health and well-being." PLOS mental health, 2(8), (2025) e0000309. doi: 10.1371/journal.pmen.0000309
- Rojas I, Barth BA, Stewart JW, et. al. "Advances in pediatric video capsule endoscopy: current applications and future directions." Frontiers in pediatrics, 13(), (2026) 1738998. doi: 10.3389/fped.2025.1738998
- McKinney E, Stewart J, Kewalramani R, et. al. "Effects of multi-herb and ashwagandha root formulas on stress modulation: a randomized, double-blind, placebo-controlled clinical study." Trials, (), (2026) . doi: 10.1186/s13063-026-09495-9
Professional Service
- CDC-NIH Committee on Chronic Fatigue in Adolescents
- NIH/NIAID Special Emphasis Panel
- Ad Hoc Reviewer CVS-A
- Reviewer, Center for Interdisciplinary Cardiovascular Sciences
