Julian M. Stewart, M.D., Ph.D., directs the Center for Hypotension, which has had NIH funding for 24 years. He is trained in medicine, integrative physiology, and computer-based biophysical methods.
Dr. Stewart's laboratory has been studying orthostatic intolerance in conscious humans for more than 20 years, with a particular focus on circulatory regulation in orthostatic intolerance (OI). Chronic OI is better known as postural tachycardia syndrome (POTS). His research has contributed to the literature regarding measurements of systemic vascular resistance, cardiac output, and venous capacitance as well as microvascular properties. Recently, Dr. Stewart's research has been focused on connections between hypocapnia, hypercapnia, hyperventilation, impaired cognition, cardiovagal baroreflexes, cerebral autoregulation, splanchnic vasoconstriction and venoconstriction, and enhanced sympathetic activity in OI patients.
Education
- Fellowship, Pediatric Cardiology, New York Hospital-Cornell University
- Residency, Physiology/Biophysics, NYU Medical Center
- M.D., University of Chicago
- Ph.D., University of Chicago
- A.B., Physics, Cornell University
- Postdoc, Pediatric Cardiology, New York Hospital-Cornell University
Areas of Expertise
- Pediatrics/Pediatric Cardiology
- Hypotension
- DOD Gulf War Syndrome
- CFS/Fibromyalgia
Research
Research interests include computational circulatory physiology, investigating vascular and cardiac properties in animal model systems, as well as during diagnostic procedures such as cardiac catheterization and flow-volume monitoring, and redistribution in critically ill infants and children. Correlative work studying the relation of cardiovascular properties to nitric oxide physiology is in progress. Recent work has also included connections of peripheral flow and muscle pump activity with osteoporosis, and contractual work with the Department of Defense related to muscular dystrophy.
Publications
- Callese T, Cusumano LR, Sparks H, et. al. "Reply to Letter to the Editor: Early intervention in knee osteoarthritis with genicular artery embolization is associated with improved clinical outcomes." European radiology, (), (2026) . doi: 10.1007/s00330-025-11952-z
- Cornell CR, Miller AE, Nieto-Caballero M, et. al. "Spatiotemporal patterns of airborne microbial communities in forest and grassland ecosystems." mBio, (), (2026) e0305725. doi: 10.1128/mbio.03057-25
- Stewart JH 4th, Niedzwiecki D, Lowe M, et. al. "Safety and feasibility of talimogene laherparepvec in peritoneal surface malignancies: Results from the TEMPO trial." Molecular therapy. Oncology, 34(1), (2025) 201111. doi: 10.1016/j.omton.2025.201111
- ATLAS Collaboration. "Transforming jet flavour tagging at ATLAS." Nature communications, 17(1), (2026) 541. doi: 10.1038/s41467-025-65059-6
- Quinto-Pozos D, McCann JP, Athreya M, et. al. "Examining signed language challenges of early- and late-exposed deaf children." Journal of deaf studies and deaf education, (), (2026) . pii: enaf083. doi: 10.1093/jdsade/enaf083
- Stewart J, Locklear T, Epling JW, et. al. "Use of Epic Signal Data to Evaluate the Impact of an "EHR Pearls" Curriculum." PRiMER (Leawood, Kan.), 9(), (2025) 56. doi: 10.22454/PRiMER.2025.153944
- Dobbs JT, Kim MS, Klopfenstein NB, et. al. "Genomic and Transcriptomic Analyses Reveal Mechanisms Associated with Pathogenesis of Fusarium annulatum and F. commune in Nursery-Grown Conifer Seedlings." Phytopathology, (), (2026) . doi: 10.1094/PHYTO-07-25-0229-R
Professional Service
- CDC-NIH Committee on Chronic Fatigue in Adolescents
- NIH/NIAID Special Emphasis Panel
- Ad Hoc Reviewer CVS-A
- Reviewer, Center for Interdisciplinary Cardiovascular Sciences
