Julian M. Stewart, M.D., Ph.D., directs the Center for Hypotension, which has had NIH funding for 24 years. He is trained in medicine, integrative physiology, and computer-based biophysical methods.
Dr. Stewart's laboratory has been studying orthostatic intolerance in conscious humans for more than 20 years, with a particular focus on circulatory regulation in orthostatic intolerance (OI). Chronic OI is better known as postural tachycardia syndrome (POTS). His research has contributed to the literature regarding measurements of systemic vascular resistance, cardiac output, and venous capacitance as well as microvascular properties. Recently, Dr. Stewart's research has been focused on connections between hypocapnia, hypercapnia, hyperventilation, impaired cognition, cardiovagal baroreflexes, cerebral autoregulation, splanchnic vasoconstriction and venoconstriction, and enhanced sympathetic activity in OI patients.
Education
- Fellowship, Pediatric Cardiology, New York Hospital-Cornell University
- Residency, Physiology/Biophysics, NYU Medical Center
- M.D., University of Chicago
- Ph.D., University of Chicago
- A.B., Physics, Cornell University
- Postdoc, Pediatric Cardiology, New York Hospital-Cornell University
Areas of Expertise
- Pediatrics/Pediatric Cardiology
- Hypotension
- DOD Gulf War Syndrome
- CFS/Fibromyalgia
Research
Research interests include computational circulatory physiology, investigating vascular and cardiac properties in animal model systems, as well as during diagnostic procedures such as cardiac catheterization and flow-volume monitoring, and redistribution in critically ill infants and children. Correlative work studying the relation of cardiovascular properties to nitric oxide physiology is in progress. Recent work has also included connections of peripheral flow and muscle pump activity with osteoporosis, and contractual work with the Department of Defense related to muscular dystrophy.
Publications
- Gary M, Hiatt M, Cole J, et. al. "HSR26-231: Diagnostic Performance of the Bexa™ Breast Exam for Detection of Breast Masses: A Prospective Single-Center Study." Journal of the National Comprehensive Cancer Network : JNCCN, 24(3.5), (2026) . pii: HSR26-231. doi: 10.6004/jnccn.2025.7187
- Radaelli J, Patel AA, Zhu M, et. al. "Critical spin fluctuations across the superconducting dome in La(2-x)Sr(x)CuO(4)." Nature communications, (), (2026) . doi: 10.1038/s41467-026-71319-w
- Dempsey R, Goldswain H, Newman J, et. al. "Characterisation of Naturally Occurring MERS-CoV Spike Mutations and Their Impact on Fusion and Neutralisation." Viruses, 18(3), (2026) . doi: 10.3390/v18030377
- Kadlaskar G, King SE, Stewart JR, et. al. "Sensory Reactivity in Children Referred for Autism Evaluation: Associations with Autism Symptoms and Adaptive Skills." Brain sciences, 16(3), (2026) . doi: 10.3390/brainsci16030310
- Mansouri A, Hart O, Aslanabadi S, et. al. "Comparative Proteomic Profiling of Responses to Standard Systemic Treatment Regimens in Pancreatic Cancer." Cells, 15(6), (2026) . doi: 10.3390/cells15060531
- Lehman A, Layton P, Mishkulin S, et. al. "Real-World Observations on the Diagnosis of Syphilis After Roll-out of Doxycycline Post-Exposure Prophylaxis." Sexually transmitted diseases, (), (2026) . doi: 10.1097/OLQ.0000000000002298
- Hakimi N, Chou KP, Stewart JL, et. al. "Computational mechanisms of learning and forgetting differentiate affective and substance use disorders." Molecular psychiatry, (), (2026) . doi: 10.1038/s41380-026-03530-6
Professional Service
- CDC-NIH Committee on Chronic Fatigue in Adolescents
- NIH/NIAID Special Emphasis Panel
- Ad Hoc Reviewer CVS-A
- Reviewer, Center for Interdisciplinary Cardiovascular Sciences
